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Radioimmunoassay for canine creatine kinase isoenzymes.

作者信息

Roberts R, Painter A

出版信息

Biochim Biophys Acta. 1977 Feb 9;480(2):521-6. doi: 10.1016/0005-2744(77)90048-1.

Abstract

Antibodies specific for the B and M subunits of creatine kinase (ATP: creatine N-phosphotransferase, EC 2.7.3.2) isoenzymes were obtained by immunization of rabbits with canine BB and MM creatine kinase. A radioimmunoassay capable of measuring picomolar amounts of creatine kinase isoenzymes has been developed which measures concentrations of intact isoenzymes rather than activity. It should aid in elucidating the metabolism and breakdown of creatine kinase isoenzymes.

摘要

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