Pearson H A, Motoyama E, Genel M, Kramer M, Zigas C J
Blood. 1977 Mar;49(3):463-5.
P50 and 2,3 DPG content of erythrocytes were determined in 25 patients with heterozygous beta thalassemia minor to assess the adaptive mechanisms to anemia. 2,3 DPG levels were appropriately elevated for the degree of anemia. However, P50 values were not proportionately increased. No correlations were noted between hemoglobin level, 2,3 DPG, or P50 and the presence of symptomatic complaints of fatigue or weakness in these heterozygous patients.
对25例杂合子轻度β地中海贫血患者测定了红细胞的P50和2,3-二磷酸甘油酸（2,3-DPG）含量，以评估对贫血的适应机制。2,3-DPG水平随贫血程度适当升高。然而，P50值并未相应增加。在这些杂合子患者中，血红蛋白水平、2,3-DPG或P50与疲劳或虚弱的症状性主诉之间未发现相关性。
