Mirabile C S, Glueck B C
Institute of Living, Hartford, Connecticut 06106.
J Neuropsychiatry Clin Neurosci. 1993 Summer;5(3):330-4. doi: 10.1176/jnp.5.3.330.
A sample of 133 candidates for antidepressant or mood-stabilizing medication treatment, with acute onset or a new phase of illness between the autumnal and vernal equinoxes, was gathered over a 3-year period from a private outpatient practice. All patients were diagnosed using DSM-III-R criteria, rated on a standard motion sickness (MS) questionnaire, and asked whether they had experienced cardinal symptoms of seasonal affective disorder (SAD). There was a positive relationship between greater MS and SAD in the entire patient sample. When a subsample of 23 patients was given a 2-week trial of phototherapy and rated for improvement, MS-susceptible patients responded better than MS-resistant patients.
在三年时间里，从一家私人门诊收集了133名抗抑郁或心境稳定剂药物治疗的候选患者样本，这些患者在秋分和春分之间病情急性发作或进入新的阶段。所有患者均根据《精神疾病诊断与统计手册》第三版修订版（DSM-III-R）标准进行诊断，使用标准晕动病（MS）问卷进行评分，并询问他们是否经历过季节性情感障碍（SAD）的主要症状。在整个患者样本中，较高的晕动病易感性与季节性情感障碍之间存在正相关关系。当对23名患者的子样本进行为期两周的光疗试验并评估改善情况时，晕动病易感患者的反应比晕动病抗性患者更好。
