Ti T K
Division of Gastrointestinal Surgery, National University Hospital.
Br J Surg. 1993 Jul;80(7):886-9. doi: 10.1002/bjs.1800800728.
A personal series of 150 patients with gastric cancer operated on over an 11-year period in Singapore is reviewed. Cancer occurred in the antrum and/or body of the stomach in 117 patients and in the cardia in 33. Gastric tumours were well or moderately differentiated adenocarcinoma in 50 patients and poorly differentiated or signet ring cell carcinoma in 100. Surgical resection was performed on 115 patients, in whom it was palliative in 47. Attempted cure by R2 radical resection was performed in 68 patients: 14 with stage I, 12 with stage II and 42 with stage III disease. There was no operative death in these 68 patients. In 82 patients operated on more than 5 years ago, five patients with carcinoma of the cardia and 28 with cancer of the gastric antrum and/or body underwent curative resection. There were 12 known 5-year survivors among the latter 28 patients; 16 of the 28 had stage III disease, six of whom survived 5 years. These results compare favourably with those of an earlier report from Singapore in which there were no 5-year survivors. The improved results probably accrue from earlier diagnosis and the current policy of radical resection.
回顾了新加坡11年间接受胃癌手术的150例患者的个人病例系列。117例患者的癌症发生在胃窦和/或胃体，33例发生在贲门。50例患者的胃肿瘤为高分化或中分化腺癌，100例为低分化或印戒细胞癌。115例患者接受了手术切除，其中47例为姑息性手术。68例患者尝试通过R2根治性切除进行治愈性治疗：14例为I期，12例为II期，42例为III期疾病。这68例患者中无手术死亡。在5年多前接受手术的82例患者中，5例贲门癌患者和28例胃窦和/或胃体癌患者接受了根治性切除。后28例患者中有12例已知存活5年；28例中有16例为III期疾病，其中6例存活5年。这些结果与新加坡早期报告的结果相比有优势，早期报告中没有5年存活者。结果的改善可能得益于早期诊断和当前的根治性切除政策。
