Suppr超能文献

缺血性和充血性心力衰竭中的冬眠心肌

The hibernating myocardium in ischaemia and congestive heart failure.

作者信息

Rahimtoola S H

机构信息

Griffith Center, University of Southern California School of Medicine, Los Angeles.

出版信息

Eur Heart J. 1993 Jul;14 Suppl A:22-6. doi: 10.1093/eurheartj/14.suppl_a.22.

Abstract

Hibernating myocardium refers to the presence of persistent myocardial and left ventricular dysfunction at rest due to reduced coronary blood flow that can be partially or completely restored to normal by myocardial revascularization. An increasing amount of data show it is most likely a downgrading of cardiac function so that blood flow and myocardial function are once again in a state of equilibrium. It has been demonstrated to occur in patients with unstable angina, chronic stable angina, acute myocardial infarction and in left ventricular dysfunction and/or congestive heart failure. Salvage of this viable myocardium by successful revascularization improves left ventricular dysfunction and probably also patient survival. Therefore, diagnosis of hibernating myocardium is important because it does not render left ventricular dysfunction a necessary contraindication to revascularization, nor does it leave the patient with chronic heart failure a candidate only for cardiac transplantation. Instead, these patients should have complete revascularization by coronary bypass surgery/percutaneous transluminal coronary angioplasty as soon as possible.

摘要

冬眠心肌是指由于冠状动脉血流减少,在静息状态下存在持续性心肌和左心室功能障碍,而通过心肌血运重建可使其部分或完全恢复正常。越来越多的数据表明,它很可能是心脏功能的一种降级,从而使血流和心肌功能再次处于平衡状态。已证实其发生于不稳定型心绞痛、慢性稳定型心绞痛、急性心肌梗死以及左心室功能障碍和/或充血性心力衰竭患者中。通过成功的血运重建挽救这种存活心肌可改善左心室功能障碍,并且可能还会提高患者生存率。因此,冬眠心肌的诊断很重要,因为它既不会使左心室功能障碍成为血运重建的必然禁忌证,也不会让慢性心力衰竭患者仅仅成为心脏移植的候选者。相反,这些患者应尽快通过冠状动脉搭桥手术/经皮冠状动脉腔内血管成形术实现完全血运重建。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验