先天性主动脉瓣狭窄与妊娠——重新评估

Congenital aortic stenosis and pregnancy--a reappraisal.

作者信息

Lao T T, Sermer M, MaGee L, Farine D, Colman J M

机构信息

Special Pregnancy Unit, Toronto Hospital, Ontario, Canada.

出版信息

Am J Obstet Gynecol. 1993 Sep;169(3):540-5. doi: 10.1016/0002-9378(93)90616-q.

DOI:10.1016/0002-9378(93)90616-q

PMID:8372858

Abstract

OBJECTIVE

This study was performed to determine the maternal and fetal outcome in pregnant patients with congenital aortic stenosis without previous valvular replacement.

STUDY DESIGN

A retrospective review of 25 pregnancies in 13 patients delivered at our centers from September 1976 to September 1992 was undertaken.

RESULTS

Five (38%) patients had associated congenital heart lesions, three (23%) had severe stenosis (echocardiographically estimated valve area < or = 0.7 cm2), two had prior open aortic valve commissurotomy, and one had balloon valvuloplasty during pregnancy. There were no maternal deaths. Of the 25 pregnancies, five (20%) resulted in therapeutic abortions. There was no perinatal mortality, preterm labor, or increased incidence of pregnancy complications or fetal growth retardation in the remaining 20 pregnancies. One infant (5%) had congenital heart disease.

CONCLUSION

Pregnancy outcome is generally satisfactory in patients with congenital aortic stenosis.

摘要

目的

本研究旨在确定既往未行瓣膜置换术的先天性主动脉瓣狭窄孕妇的母婴结局。

研究设计

对1976年9月至1992年9月在我们中心分娩的13例患者的25次妊娠进行回顾性研究。

结果

5例（38%）患者合并先天性心脏病变，3例（23%）有严重狭窄（超声心动图估计瓣膜面积≤0.7平方厘米），2例曾行开放性主动脉瓣交界切开术，1例在孕期行球囊瓣膜成形术。无孕产妇死亡。25次妊娠中，5例（20%）进行了治疗性流产。其余20次妊娠中无围产儿死亡、早产，妊娠并发症或胎儿生长受限的发生率也未增加。1例婴儿（5%）患有先天性心脏病。