Ottaviani E, Franchini A, Franceschi C
Department of Animal Biology, University of Modena, Italy.
Biochem Biophys Res Commun. 1993 Sep 15;195(2):984-8. doi: 10.1006/bbrc.1993.2141.
The presence of a variety of cytokine-like molecules (IL-1 alpha, IL-1 beta, IL-2, IL-6, TNF-alpha) in the hemocytes of two molluscs, i.e., Planorbarius corneus and Viviparus ater, is reported. These molecules are present only in hemocytes with phagocytic activity. These data, together with recent reports on the presence of cytokine-like molecules in other invertebrates, suggest that cytokines are important, ancestral and functionally conserved molecules.
据报道，在两种软体动物即角扁卷螺和黑瓶螺的血细胞中存在多种细胞因子样分子（白细胞介素-1α、白细胞介素-1β、白细胞介素-2、白细胞介素-6、肿瘤坏死因子-α）。这些分子仅存在于具有吞噬活性的血细胞中。这些数据，连同最近关于其他无脊椎动物中存在细胞因子样分子的报道，表明细胞因子是重要的、原始的且功能保守的分子。
