Carroll B, Richardson J T, Thompson P
Department of Human Sciences, Brunel University, Uxbridge, Middlesex, UK.
Brain Cogn. 1993 Jul;22(2):230-43. doi: 10.1006/brcg.1993.1036.
It has been suggested that olfactory information processing is impaired in patients with temporal lobe epilepsy. However, the existing evidence is not wholly in accordance with this notion. Patients with epileptogenic foci in the left temporal lobe, the right temporal lobe, or other brain regions were compared with normal control subjects in the identification and retention of common odors. All three patient groups were substantially and equally impaired in verbally labelling the odors in question. The patients with epilepsy associated with the left temporal lobe or with nontemporal regions showed no sign of any impairment on a test of immediate recognition memory for common odors. However, the patients with epilepsy associated with the right temporal lobe showed a specific disturbance in their retention of nameable odors. It is suggested that the latter patients were selectively impaired in their retrieval of the episodic memories which provide the context for the encoding of distinctive odors.
有人提出，颞叶癫痫患者的嗅觉信息处理受损。然而，现有证据并不完全支持这一观点。将左侧颞叶、右侧颞叶或其他脑区存在致痫灶的患者与正常对照受试者在常见气味的识别和记忆方面进行了比较。所有三组患者在对相关气味进行言语标记时均受到显著且同等程度的损害。与左侧颞叶或非颞叶区域相关的癫痫患者在对常见气味的即时识别记忆测试中未表现出任何受损迹象。然而，与右侧颞叶相关的癫痫患者在可命名气味的记忆方面表现出特定障碍。有人认为，后一组患者在检索为独特气味编码提供背景的情景记忆方面存在选择性受损。
