• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The formation of phenylethane-1,2-diol 2-acetate in the metabolism of styrene oxide by rabbit liver microsomes in vitro.

作者信息

Battistini C, Bellucci G, Mastrorilli E

出版信息

Xenobiotica. 1979 Jan;9(1):57-61. doi: 10.3109/00498257909034704.

DOI:10.3109/00498257909034704
PMID:83739
Abstract
  1. Phenylethane-1,2-diol 2-acetate has been isolated from the incubation of styrene oxide or styrene diol with liver microsomes of phenobarbital-pretreated rabbits. 2. Observed ratios of phenylethane-1,2-diol to its 2-acetate in the incubation mixtures ranged between 19 : 1 and 5 : 1 with different microsomal preparations and different periods of incubation. 3. The formation of phenylethane-1,2-diol 2-acetate may be a source of errors in the radiometric determination of epoxide hydrase activity in microsomes.
摘要

相似文献

1
The formation of phenylethane-1,2-diol 2-acetate in the metabolism of styrene oxide by rabbit liver microsomes in vitro.
Xenobiotica. 1979 Jan;9(1):57-61. doi: 10.3109/00498257909034704.
2
The metabolism of antifertility steroids. The in virto metabolism of chlormadinone acetate.抗生育甾体的代谢。醋酸氯地孕酮的体外代谢。
Drug Metab Dispos. 1974 May-Jun;2(3):214-20.
3
Arene oxides in styrene metabolism, a new perspective in styrene toxicity?苯乙烯代谢中的芳烃氧化物，苯乙烯毒性的新视角？
Scand J Work Environ Health. 1978;4 Suppl 2:67-77.
4
Microsomal styrene mono-oxygenase and styrene epoxide hydrase activities in rats.大鼠微粒体苯乙烯单加氧酶和苯乙烯环氧化物水解酶活性
Xenobiotica. 1976 Oct;6(10):585-91. doi: 10.3109/00498257609151671.
5
Characterization of rat lung epoxide (styrene oxide) hydrase with a modified radioactive assay of improved sensitivity.采用改进的放射性检测法对大鼠肺环氧物（氧化苯乙烯）水化酶进行特性分析，该检测法灵敏度更高。
Cancer Res. 1977 Apr;37(4):1075-82.
6
Biosynthesis of 16 alpha, 17 alpha-epoxy-4-androsten-3-one in rat liver microsomes.大鼠肝微粒体中16α,17α-环氧-4-雄烯-3-酮的生物合成
Acta Endocrinol (Copenh). 1980 Sep;95(1):58-66.
7
Stereoselectivity of styrene oxidation in microsomes and in purified cytochrome P-450 enzymes from rat liver.
J Pharmacol Exp Ther. 1989 Feb;248(2):492-7.
8
Stereochemistry in the oxidative metabolism of styrene by hepatic microsomes.肝微粒体对苯乙烯氧化代谢中的立体化学
Biochem Pharmacol. 1981 Jun 15;30(12):1695-8. doi: 10.1016/0006-2952(81)90399-3.
9
Hepatic and extrahepatic metabolism of 14C-styrene oxide.14C-氧化苯乙烯的肝脏和肝外代谢
Environ Health Perspect. 1976 Oct;17:135-44. doi: 10.1289/ehp.7617135.
10
Metabolism and mutagenicity of styrene.苯乙烯的代谢与致突变性。
Scand J Work Environ Health. 1978;4 Suppl 2:142-55.

引用本文的文献

1
Development of enantioselective polyclonal antibodies to detect styrene oxide protein adducts.用于检测环氧苯乙烷蛋白加合物的对映体选择性多克隆抗体的研制。
Anal Chem. 2009 Apr 1;81(7):2668-77. doi: 10.1021/ac8023262.
2
Styrene-7,8-oxide in blood of workers exposed to styrene.接触苯乙烯的工人血液中的苯乙烯-7,8-氧化物。
Arch Toxicol. 1994;68(8):524-7. doi: 10.1007/s002040050107.