Shevelev O A, Sokov E L
Biull Eksp Biol Med. 1993 Jun;115(6):587-9.
Acute tests in mature cats, demonstrated, evoked potentials in the cortex and medial center of the thalamus resulting from test irritation of sciatic nerves and conditioning irritations of intra-osseous receptors. The test proved that electro-irritation of intra-osseous receptors as well as higher intra-osseous pressure caused by the impregnation of physiological solution into the bone facilitated afferent reactions during threshold electrostimulation of sciatic nerves. The results of these experiments were compared to those of clinical monitoring of patients with radicular syndromes of osteochondrosis after intra-osseous blockades which led the authors to suggest a hypothesis about trigger mechanisms of neuralgias, based on segmental alleviation of nociceptive afferentation resulting from overstimulation of intra-osseous receptors.
在成年猫身上进行的急性试验表明，对坐骨神经进行试验性刺激以及对骨内感受器进行条件性刺激时，在皮质和丘脑内侧中枢诱发了电位。该试验证明，对骨内感受器进行电刺激以及向骨内注入生理溶液所导致的较高骨内压，在对坐骨神经进行阈下电刺激时促进了传入反应。将这些实验结果与骨内阻滞术后患有骨软骨病神经根综合征患者的临床监测结果进行了比较，这使作者基于骨内感受器过度刺激导致伤害性传入的节段性减轻，提出了关于神经痛触发机制的假说。
