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利多卡因肌内注射和骨内触发点注射治疗退行性腰椎管狭窄减压术后残留慢性疼痛的疗效

Efficiency of Lidocaine Intramuscular and Intraosseous Trigger Point Injections in the Treatment of Residual Chronic Pain after Degenerative Lumbar Spinal Stenosis Decompression Surgery.

作者信息

Al-Zamil Mustafa, Kulikova Natalia G, Shnayder Natalia A, Korchazhkina Natalia B, Petrova Marina M, Mansur Tatyana I, Blinova Vasilissa V, Babochkina Zarina M, Vasilyeva Ekaterina S, Zhhelambekov Ivan V

机构信息

Department of Physiotherapy, Faculty of Continuing Medical Education, Peoples' Friendship University of Russia, 117198 Moscow, Russia.

Department of Sports Medicine and Medical Rehabilitation, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.

出版信息

J Clin Med. 2024 Sep 13;13(18):5437. doi: 10.3390/jcm13185437.

Abstract

: Despite the long-term use of intramuscular and intraosseous lidocaine trigger point injections (LTPI) in the treatment of patients with low back pain, there have been no studies examining their efficiency in treatment of residual pain after degenerative lumbar spinal stenosis (DLSS) decompression surgery. The purpose of our research is to examine the LTPI efficiency in the treatment of residual lumbar pain after DLSS decompression surgery and to compare the analgesic and recovery effects of intramuscular and intraosseous LTPI administered in the L4-S1 region and in the posterior superior iliac spine (PSIS) after treatment and during four months of follow-up. : We observed 99 patients (F:50, M:49) aged 42 to 59 years with residual neurological disorders after DLSS decompression surgery. In all patients, the pain syndrome exceeded 6 points on the VAS and averaged 7.2 ± 0.11 points. The control group ( = 21) underwent only pharmacotherapy. In addition to pharmacotherapy, the LTPI group underwent intramuscular LTPI in L4-S1 ( = 20), intramuscular LTPI in the PSIS ( = 19), intraosseous LTPI in L5, S1 ( = 20), and intraosseous LTPI in the PSIS ( = 19). A neurological examination was carried out before treatment, 7 days after completion of treatment, and at the end of the second and fourth months of the follow-up period. : In the control group, intramuscular LTPI in L4-S1 subgroup, intramuscular LTPI in PSIS subgroup, intraosseous LTPI in L5, S1 subgroup, and intraosseous LTPI in PSIS subgroup, the severity of pain decreased after treatment by 27.1% ( ≤ 0.05), 41.7% ( ≤ 0.01), 50.7% ( ≤ 0.01), 69% ( ≤ 0.01), and 84.7% ( ≤ 0.01), respectively, and at the end of the second month of follow-up, by 14.3% ( > 1), 29.2% ( ≤ 0.05), 38% ( ≤ 0.01), 53.5% ( ≤ 0.01), and 72.2% ( ≤ 0.01), respectively. Reduction of neurogenic claudication, regression of sensory deficit, increase of daily step activity, and improvement of quality of life after treatment were noted in intramuscular LTPI subgroups by 19.6% ( ≤ 0.05), 36.4 ( ≤ 0.05), 40.3% ( ≤ 0.01), and 21.0% ( ≤ 0.05), respectively, and in interosseous LTPI subgroups by 48.6% ( ≤ 0.01), 67.4% ( ≤ 0.01), 68.3% ( ≤ 0.01), and 46% ( ≤ 0.01), respectively. : LTPI is highly effective in the treatment of patients with residual pain after DLSS decompression surgery. High analgesic effect, significant regression of sensory deficits and gait disorders, and remarkable improvement of daily step activity and quality of life are noted not only after the end of LTPI treatment but also continue for at least 2 months after treatment. Intraosseous LTPI is more effective than intramuscular LTPI by 92%, and LTPI in PSIS is more effective than LTPI in L4-S1 by 28.6%.

摘要

尽管长期使用肌肉注射和骨内注射利多卡因触发点注射(LTPI)来治疗腰痛患者,但尚无研究探讨其在退行性腰椎管狭窄症(DLSS)减压手术后残余疼痛治疗中的效果。我们研究的目的是检验LTPI在DLSS减压手术后残余腰部疼痛治疗中的效果,并比较在L4 - S1区域和髂后上棘(PSIS)进行肌肉注射和骨内注射LTPI在治疗后及四个月随访期间的镇痛和恢复效果。:我们观察了99例年龄在42至59岁之间、DLSS减压手术后有残余神经功能障碍的患者(女性50例,男性49例)。所有患者的疼痛综合征在视觉模拟评分(VAS)上超过6分,平均为7.2±0.11分。对照组(n = 21)仅接受药物治疗。除药物治疗外,LTPI组在L4 - S1进行肌肉注射LTPI(n = 20),在PSIS进行肌肉注射LTPI(n = 19),在L5、S1进行骨内注射LTPI(n = 20),在PSIS进行骨内注射LTPI(n = 19)。在治疗前、治疗结束后7天以及随访期第二个月末和第四个月末进行神经学检查。:在对照组、L4 - S1亚组肌肉注射LTPI、PSIS亚组肌肉注射LTPI、L5、S1亚组骨内注射LTPI以及PSIS亚组骨内注射LTPI中,治疗后疼痛严重程度分别降低了27.1%(P≤0.05)、41.7%(P≤0.01)、50.7%(P≤0.01)、69%(P≤0.01)和84.7%(P≤0.01),在随访期第二个月末分别降低了14.3%(P>0.1)、29.2%(P≤0.05)、38%(P≤0.01)、53.5%(P≤0.01)和72.2%(P≤0.01)。在肌肉注射LTPI亚组中,治疗后神经源性间歇性跛行的减轻、感觉障碍的消退、每日步数活动的增加以及生活质量的改善分别为19.6%(P≤0.05)、36.4(P≤0.05)、40.3%(P≤0.01)和21.0%(P≤0.05),在骨内注射LTPI亚组中分别为48.6%(P≤0.01)、67.4%(P≤0.01)、68.3%(P≤0.01)和46%(P≤0.01)。:LTPI在治疗DLSS减压手术后残余疼痛的患者中非常有效。不仅在LTPI治疗结束后,而且在治疗后至少2个月内,都观察到了高镇痛效果、感觉障碍和步态障碍的显著消退以及每日步数活动和生活质量的显著改善。骨内注射LTPI比肌肉注射LTPI有效92%,PSIS部位的LTPI比L4 - S1部位的LTPI有效28.6%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe9/11432395/c84c43f6e4a2/jcm-13-05437-g001.jpg

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