Kommoss F, DeGregorio G, Strittmatter B, Pfisterer J, Karck U, Zahradnik H P, Breckwoldt M
Universitäts-Frauenklinik Freiburg.
Geburtshilfe Frauenheilkd. 1993 Aug;53(8):564-7. doi: 10.1055/s-2007-1022935.
An increasing percentage of patients with uterine leiomyomas was observed in the Department of Obstetrics, University of Freiburg, on comparing the years 1970-79 (0.25%) and 1980-89 (0.64%). While first trimester bleeding, pain and premature labour, being typical obstetrical complications, were encountered in a comparable frequency, atonic bleeding was observed more often during the nineteen-eighties. Pain and premature labour were often present, if the leiomyomas were large, irrespective of both their number or localization. Atonic bleeding was observed more frequently, if large leiomyomas were present. A correlation between the presence of uterine leiomyomas and placental deficiency, premature birth, and EPH gestosis seems uncertain. The total complication rate among all pregnant patients with uterine leiomyomas was 65% from 1980-89. The Caesarean section rate among patients with uterine leiomyomas increased during the evaluated time span, and reached 51% during the 1980's, as compared to a general frequency of Caesarean sections of 19% during the latter time period; this increase in frequency seems to be rather in keeping with a generally increasing Caesarean section rate as opposed to a changing indication for surgery in patients with myomas. The myomas themselves caused Caesarean sections in 50% of cases, while in the remaining 50% of patients, Caesarean sections were performed for general obstetrical reasons. The probability to be delivered by Caesarean section was especially high amongst patients with multiple myomas or with an isthmic myoma. Our study supports a conservative approach in the case of pregnancy and uterine leiomyomas.
通过比较弗莱堡大学妇产科1970 - 1979年(0.25%)和1980 - 1989年(0.64%)的数据发现,子宫平滑肌瘤患者的比例呈上升趋势。虽然早孕出血、疼痛和早产这些典型的产科并发症出现的频率相当,但在20世纪80年代宫缩乏力性出血更为常见。如果平滑肌瘤较大,无论其数量或位置如何,疼痛和早产往往都会出现。如果存在大的平滑肌瘤,宫缩乏力性出血更为频繁。子宫平滑肌瘤与胎盘功能不全、早产和妊娠高血压综合征之间的相关性似乎并不确定。1980 - 1989年,所有患有子宫平滑肌瘤的孕妇的总并发症发生率为65%。在评估的时间段内,子宫平滑肌瘤患者的剖宫产率有所上升,在20世纪80年代达到了51%,而在此期间剖宫产的总体发生率为19%;这种频率的增加似乎与剖宫产率普遍上升更为一致,而不是肌瘤患者手术指征的改变。肌瘤本身导致剖宫产的病例占50%,而在其余50%的患者中,剖宫产是出于一般产科原因进行的。多发性肌瘤或峡部肌瘤患者剖宫产的概率尤其高。我们的研究支持对妊娠合并子宫平滑肌瘤采取保守治疗方法。