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Indolinonic and quinolinic aminoxyls as protectants against oxidative stress.

作者信息

Antosiewicz J, Bertoli E, Damiani E, Greci L, Popinigis J, Przybylski S, Tanfani F, Wozniak M

机构信息

Academy of Physical Education, Department of Bioenergetics and Medical Academy, Gdansk, Poland.

出版信息

Free Radic Biol Med. 1993 Aug;15(2):203-8. doi: 10.1016/0891-5849(93)90060-8.

Abstract

A study on thermally and peroxyl radical induced oxidation of linolenic acid micelles in the presence of different concentrations of aminoxyls was carried out in order to test their efficiency as antioxidants in lipid peroxidation. The extent of peroxidation was measured by the malondialdehyde (MDA) produced and by oxygen consumption evaluated using an oxygraph. The results obtained indicate that indolinonic and quinolinic aminoxyls synthesized by us could be used as effective antioxidants in biological systems.

摘要

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