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[女童硬化性苔藓——女性外阴肿瘤发生的风险因素]

[Lichen sclerosus in girls--risk group for development of vulvar neoplasms in women].

作者信息

Sowińska E, Lazar W, Menkiszak J, Zielińska D, Wydra E, Rzepka-Górska I

机构信息

Kliniki Ginekologii Operacyjnej IPG PAM, Szczecinie.

出版信息

Ginekol Pol. 1993 Jun;64(6):305-9.

PMID:8375705
Abstract

Lichen sclerosus is one of the vulvar dystrophy, which is rare at children and young women. 20 girls, aged 3 to 14 years, with clinical and histopathological diagnosis--lichen sclerosus without dysplastic lesions--were under the control of The Gynecological Outpatient Clinic of Children and Girls in Szczecin. They were treated with estrogens (estriol with vitamin A--ointment) and vitamin A rich diet. Anti-inflammatory treatment was employed if necessary. After long-term treatment at 8 girls the total recovery was obtained, at 2, clinical symptoms decreased. Other girls are under clinical observation as before. The girls with lichen sclerosus are a risk group of vulvar carcinoma development in mature age.

摘要

硬化性苔藓是外阴营养不良的一种,在儿童和年轻女性中较为罕见。20名年龄在3至14岁之间、经临床和组织病理学诊断为无发育异常病变的硬化性苔藓的女孩,在什切青儿童及女童妇科门诊接受随访。她们接受了雌激素(雌三醇加维生素A——软膏)治疗以及富含维生素A的饮食。必要时采用抗炎治疗。经过长期治疗,8名女孩完全康复,2名女孩临床症状减轻。其他女孩仍如之前一样接受临床观察。患有硬化性苔藓的女孩在成年后患外阴癌的风险较高。

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