Goodarzi M, Shier N H, Ogden J A
Shriners Hospital for Crippled Children, Tampa, FL 33612.
J Pediatr Orthop. 1993 Sep-Oct;13(5):663-7.
We compared epidural and patient-controlled analgesia using morphine for pain relief during the first 30 h after orthopaedic surgery to examine whether intermittent epidural morphine (EM) offered a clinical advantage over patient-controlled analgesia in children. Forty patients were assigned randomly to receive either EM or morphine by the patient-controlled analgesia technique. In the special care unit, trained observers evaluated the patient's level of postoperative pain with a standardized objective pain scale. The differences in pain scores among the groups were compared. The two groups were not significantly different in age, weight, duration of operation, or anesthesia. There was no significant difference in quality of pain relief except for the amount of medicine required to control postoperative pain and the incidence of side effects between the two groups.
我们比较了骨科手术后最初30小时内使用吗啡进行硬膜外镇痛和患者自控镇痛,以研究间歇性硬膜外吗啡(EM)在儿童中是否比患者自控镇痛具有临床优势。40名患者被随机分配接受EM或通过患者自控镇痛技术使用吗啡。在特别护理病房,训练有素的观察者用标准化的客观疼痛量表评估患者的术后疼痛程度。比较了各组之间的疼痛评分差异。两组在年龄、体重、手术时间或麻醉方面无显著差异。除了控制术后疼痛所需的药物量和两组之间的副作用发生率外,两组在疼痛缓解质量方面无显著差异。