Hubler W R
Cutis. 1977 Jan;19(1):86-8.
A case of cutaneous hypopigmented macules localized above deep dermal and subcutaneous sarcoid granulomas in a patient with systemic sarcoidosis is presented. Melanin was only sparsely distributed in the upper stratum malpighii. Hypopigmentation is an unusual manifestation of sarcoidosis. With an armamentarium of clinical observation, dermatologists may suspect a hypomelanotic cutaneous diadem overlying a palpable dermal mass to be a visual vignette of a sarcoidal montage requiring diagnostic biopsy.
本文报告了一例全身性结节病患者,其皮肤色素减退斑位于真皮深层和皮下结节病肉芽肿上方。黑色素仅稀疏分布于马尔皮基上层。色素减退是结节病的一种不寻常表现。通过一系列临床观察,皮肤科医生可能会怀疑覆盖在可触及的真皮肿物上的色素减退性皮肤王冠是结节病组合的一种视觉表现,需要进行诊断性活检。