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[无缺血性心脏病临床表现的糖尿病患者的无症状心肌缺血]

[Silent myocardial ischemia in patients with diabetes mellitus without the clinical manifestations of ischemic heart disease].

作者信息

Zharov E i, Kazankov Iu N, Grigor'ev M Iu

出版信息

Kardiologiia. 1993;33(6):16-8.

PMID:8377356
Abstract

A total of 40 patients with diabetes mellitus without anginal episodes and equivalents were studied. 24-hour monitoring identified 2 groups of patients: (1) 13 patients with recorded silent myocardial ischemic episodes and (2) 23 patients without episodes. Four patients were found to have stress-echocardiographic silent myocardial ischemia. Silent myocardial ischemia was detected in 42.5% of patients with diabetes mellitus. The patients from Group 1 exhibited more frequently Type II diabetes mellitus whose duration was over 9 years and concurrent retino- and polyneuropathies. There was a relationship between silent myocardial ischemia to heart failure and myocardial hypertrophy as evidenced by two-dimensional echocardiography. The patients from Group 1 had a higher pain sensitivity threshold than those from Group 2. Autonomic polyneuropathy was observed in 46% of Group 1 patients and in 21% of Group 2 patients.

摘要

共研究了40例无心绞痛发作及类似情况的糖尿病患者。24小时监测确定了两组患者:(1)13例有记录的无症状心肌缺血发作患者和(2)23例无发作患者。发现4例患者有负荷超声心动图无症状心肌缺血。42.5%的糖尿病患者检测到无症状心肌缺血。第1组患者更常表现为病程超过9年的II型糖尿病以及并发视网膜病变和多发性神经病变。二维超声心动图显示,无症状心肌缺血与心力衰竭和心肌肥厚之间存在关联。第1组患者的疼痛敏感性阈值高于第2组患者。第1组46%的患者和第2组21%的患者观察到自主神经多发性神经病变。

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