Abe K, Yorifuji S, Nishikawa Y
Department of Neurology, Osaka University Medical School, Japan.
Neuroradiology. 1993;35(6):410-1. doi: 10.1007/BF00602817.
To study degeneration in the central nervous system in amyotrophic lateral sclerosis (ALS), we studied four patients using single photon emission tomography (SPECT) and magnetic resonance imaging (MRI). MRI demonstrated high intensity along the pyramidal tract on T2-weighted images in two. SPECT demonstrated reduced isotope uptake restricted to the motor area. While the cause of degeneration of the cortical neurons in the motor area is unknown, SPECT is useful for detecting the degeneration in patients with ALS.
为研究肌萎缩侧索硬化症（ALS）患者中枢神经系统的退变情况，我们对4例患者进行了单光子发射断层扫描（SPECT）和磁共振成像（MRI）检查。MRI显示，2例患者在T2加权图像上沿锥体束有高强度信号。SPECT显示，仅运动区的同位素摄取减少。虽然运动区皮质神经元退变的原因尚不清楚，但SPECT有助于检测ALS患者的神经元退变情况。
