Udaka F, Sawada H, Seriu N, Shindou K, Nishitani N, Kameyama M
Department of Neurology, Sumitomo Hospital, Osaka, Japan.
Neuroradiology. 1992;34(5):389-93. doi: 10.1007/BF00596496.
MRI was performed in 21 patients and single photon emission computed tomography (SPECT) with N-isopropyl-p-123I iodoamphetamine in 16 patients, to visualize upper motor neurone lesions in amyotrophic lateral sclerosis. T2-weighted MRI revealed high signal along the course of the pyramidal tract in the internal capsule and cerebral peduncle in 4 of 21 patients. SPECT images were normal in 4 patients, but uptake was reduced in the cerebral cortex that includes the motor area in 11.
