Kitching P A, Gibbs A R
Department of Pathology, University Hospital of Wales, Cardiff, U.K.
Pathol Res Pract. 1993 Jun;189(5):594-6; discussion 597-600. doi: 10.1016/S0344-0338(11)80375-4.
We describe an unusual case of pulmonary involvement by mycosis fungoides in a 31-year-old woman. Disseminated disease had developed despite cutaneous irradiation and systemic combination chemotherapy. Microscopy of biopsied tumour deposits in the lung showed a polymorphous, angiocentric lymphoid infiltrate, including atypical cells with convoluted nuclei which displayed a T-cell phenotype. Numerous epithelioid granulomas were also present. These histological appearances represent an unusual pattern of pulmonary involvement by disseminated mycosis fungoides.
