Westenberg H G, Den Boer J A
Department of Biological Psychiatry, Academic Hospital Utrecht, The Netherlands.
Pharmacopsychiatry. 1993 May;26 Suppl 1:30-3. doi: 10.1055/s-2007-1021803.
Research conducted during the past decade has resulted in a range of options for treating panic disorder. Favorable responses to tricyclic antidepressants, monoamine oxidase inhibitors, selective serotonin reuptake inhibitors, and high-potency benzodiazepines have been reported. When costs and benefits are taken into account, the selective serotonin uptake inhibitors currently seem to be the treatment of choice. Studies with serotonin agonists and antagonists are as of yet disappointing. The introduction of cholecystokinin antagonists has opened up intriguing new areas of research. This paper reviews those findings and developments.
在过去十年中进行的研究产生了一系列治疗惊恐障碍的方法。据报道，三环类抗抑郁药、单胺氧化酶抑制剂、选择性5-羟色胺再摄取抑制剂和高效苯二氮卓类药物都有良好疗效。当考虑到成本和效益时，选择性5-羟色胺再摄取抑制剂目前似乎是首选治疗方法。5-羟色胺激动剂和拮抗剂的研究至今令人失望。胆囊收缩素拮抗剂的引入开辟了有趣的新研究领域。本文综述了这些发现和进展。
