一只Fischer-344大鼠的多囊性腹膜间皮瘤
Multicystic peritoneal mesothelioma in a Fischer-344 rat.
作者信息
Shibuya K, Tajima M, Yamate J
机构信息
Nippon Institute for Biological Science, Tokyo, Japan.
出版信息
Toxicol Pathol. 1993;21(1):87-90. doi: 10.1177/019262339302100111.
A spontaneous multicystic peritoneal mesothelioma was detected in a 108-wk-old male Fischer-344/DuCrj rat. Grossly, a tumor containing numerous, semi-transparent, variously sized, thin-walled cysts was found on the splenic serosal surface. Microscopically, each cyst was surrounded by variable amounts of loose connective tissue. The luminal and free surfaces of the cysts were covered by a single layer of flattened or cuboidal mesothelial cells. No metastases were detected in any of the other organs. Diagnosis was supported by immunohistochemistry and ultrastructural features.
在一只108周龄的雄性Fischer-344/DuCrj大鼠中检测到自发性多囊性腹膜间皮瘤。大体观察，在脾脏浆膜表面发现一个肿瘤，其包含许多半透明、大小各异、薄壁的囊肿。显微镜下，每个囊肿被不同数量的疏松结缔组织包围。囊肿的腔面和游离面被单层扁平或立方间皮细胞覆盖。在任何其他器官均未检测到转移。免疫组织化学和超微结构特征支持该诊断。
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