Evers K G, Krüger J, Hägele R, Haase W, Leven B
Eur J Pediatr. 1977 Feb 21;124(3):199-205. doi: 10.1007/BF00452111.
Thirteen patients with primary immunodeficiency disorders and their twenty-five healthy first-degree relatives were tissue typed and their HLA make-up was compared with that of a normal control population. HLA-A2 occured in 92.3% of patients as opposed to 60.8% in the control group (P less than 0.02), HLA-A9 in 7.6% vs. 25% (P less than 0.02) and HLA-B8 in 0% vs. 21% (P less than 0.04). One of the patients with severe combined immunodeficiency showed one "extraneous" HLA specifity.
对13例原发性免疫缺陷病患者及其25名健康的一级亲属进行了组织分型,并将他们的HLA组成与正常对照人群进行了比较。HLA - A2在92.3%的患者中出现,而对照组为60.8%(P<0.02);HLA - A9在患者中为7.6%,对照组为25%(P<0.02);HLA - B8在患者中为0%,对照组为21%(P<0.04)。1例重症联合免疫缺陷患者表现出一种“额外的”HLA特异性。