Ackermann R, Müller H A
Eur Urol. 1977;3(1):29-34. doi: 10.1159/000472050.
Transrectal aspiration biopsy of the prostate has been recommended as method of choice for morphological diagnosis of prostatic malignancies. It is less inconvenient to the patient and with hardly any complications. A retrospective analysis of 645 simultaneous perineal punch biopsies and transrectal aspiration biopsies was carried out in order to elicit whether prostatic carcinoma can be detected with transrectal aspiration biopsy as frequently as with perineal punch biopsy, and whether a cytological diagnosis of prostatic cancer is reliable. Carcinoma of the prostate was found in a total of 39.1% either with both techniques or with only one of them. A concordant diagnosis has been obtained in only 25.1%. Prostatic carcinoma was diagnosed more often by perineal punch biopsy (36.1%) than by transrectal aspiration biopsy (27.7%). However, the diagnosis has been missed by perineal punch biopsy in 2.6% of the cases. Doubtful results and unsatisfactory preparations have been observed more frequently after transrectal aspiration biopsies. Definite 'false-positive' cystological findings have not been detected. Thus, cytological evaluation of aspirated prostatic cells appears reliable. A definite morphological diagnosis can be expected with this technique. Simultaneous application of perineal punch biopsy and transrectal aspiration biopsy can be recommended in order to diagnose prostatic carcinoma with a higher frequency.
经直肠前列腺穿刺活检已被推荐为前列腺恶性肿瘤形态学诊断的首选方法。它给患者带来的不便较少，且几乎没有任何并发症。对645例同时进行的会阴穿刺活检和经直肠穿刺活检进行了回顾性分析，以确定经直肠穿刺活检能否像会阴穿刺活检一样频繁地检测出前列腺癌，以及前列腺癌的细胞学诊断是否可靠。两种技术或仅其中一种技术共发现39.1%的前列腺癌。仅25.1%的病例获得了一致诊断。会阴穿刺活检诊断前列腺癌的比例（36.1%）高于经直肠穿刺活检（27.7%）。然而，2.6%的病例会阴穿刺活检漏诊。经直肠穿刺活检后更频繁地观察到可疑结果和不满意的标本。未检测到明确的“假阳性”细胞学结果。因此，对吸出的前列腺细胞进行细胞学评估似乎是可靠的。使用该技术有望获得明确的形态学诊断。为了更高频率地诊断前列腺癌，建议同时应用会阴穿刺活检和经直肠穿刺活检。
