Pellegrini C A, Leichter R, Patti M, Somberg K, Ostroff J W, Way L
Department of Surgery, University of California, San Francisco.
Ann Thorac Surg. 1993 Sep;56(3):680-2. doi: 10.1016/0003-4975(93)90950-m.
We treated 24 patients with achalasia using thoracoscopic (22 patients) or laparoscopic (2 patients) esophagomyotomy. The only operative complications were mucosal lacerations, which occurred in 3 patients and required conversion to an open procedure in 2. Twenty-two (91%) patients were eating by the second postoperative day. Analgesics were only required for the management of pain from the chest tube, which remained in place for a median time of 24 hours. The median postoperative hospital stay was 3 days (range, 20 to 14 days). The myotomy proved to be incomplete in the first 3 patients, who required a second myotomy; this was done laparoscopically in 2. One patient had a paraesophageal hernia repaired 6 months after the myotomy, and 1 patient required an esophagectomy 1 year after the myotomy for a large nonfunctioning esophagus. Late follow-up showed that swallowing was excellent in 17 (71%) and fair to good in 4 (17%). Sixteen (66%) of these 24 patients have regained their original weight. Thus, excellent to good results were ultimately obtained in nearly 90% of the patients. These results suggest that esophageal myotomy performed using minimally invasive techniques appears to be the treatment of choice for achalasia.
我们采用胸腔镜手术(22例患者)或腹腔镜手术(2例患者)对24例贲门失弛缓症患者进行了食管肌层切开术。仅有的手术并发症为黏膜撕裂伤,3例患者出现该并发症,其中2例需转为开放手术。22例(91%)患者术后第二天即可进食。仅在处理胸管所致疼痛时需要使用镇痛药,胸管留置的中位时间为24小时。术后住院时间的中位数为3天(范围为2~14天)。最初的3例患者肌层切开术证实不完全,需要再次进行肌层切开术;其中2例通过腹腔镜完成。1例患者在肌层切开术后6个月进行了食管旁疝修补术,1例患者在肌层切开术后1年因食管巨大且无功能而接受了食管切除术。后期随访显示,17例(71%)患者吞咽功能极佳,4例(17%)患者吞咽功能良好至尚可。这24例患者中有16例(66%)恢复到了原来的体重。因此,近90%的患者最终获得了极佳至良好的治疗效果。这些结果表明,采用微创技术进行食管肌层切开术似乎是贲门失弛缓症的首选治疗方法。