Coutinho E M, Da Silva A R, Kraft H G
Int J Fertil. 1976(2):103-8.
The contraceptive action of silastic implants containing a new progestion ST-1435 was investigated in 285 women of reproductive age. A group of 52 women (group A) received three capsules containing each 35 mg of the steroid. A second group of 48 women (group B) received four capsules and a third and larger group of 185 women (group C) received five capsules. No pregnancies occurred during 530 months of use in group A. In 502 months of use recorded for group B, one pregnancy occurred. In group C, 2.142 months were recorded. One pregnancy was reported at the end of 11 months of use and another at the end of 19 months of use. Alterations in the pattern of menstrual bleeding was the most common side effect.
对285名育龄妇女研究了含新型孕激素ST - 1435的硅橡胶植入物的避孕作用。一组52名妇女（A组）接受了3粒胶囊，每粒含35毫克该类固醇。第二组48名妇女（B组）接受了4粒胶囊，第三组也是人数更多的一组185名妇女（C组）接受了5粒胶囊。A组在530个月的使用期内未发生妊娠。B组记录的502个月使用期内发生了1次妊娠。C组记录的使用期为2142个月。在使用11个月结束时报告了1次妊娠，在使用19个月结束时又报告了1次妊娠。月经出血模式改变是最常见的副作用。
