Zimmermann P, Takala T, Pöyhönen L, Punnonen R
Department of Obstetrics and Gynecology, University Hospital, Tampere, Finland.
J Clin Ultrasound. 1993 Feb;21(2):109-13. doi: 10.1002/jcu.1870210206.
Thyroid function and ultrasonographically determined thyroid volume were studied in nine pregnant women with diagnosed autoimmune thyroid disease at regular intervals during pregnancy and two months after delivery. The results were compared to the findings in ten healthy pregnant women. In ultrasound examinations seven of the patients showed definite morphological changes such as hypoechogeneity and inhomogeneity of the thyroid gland, which did not change during the course of pregnancy nor during the post-partum period of eight weeks. There were no morphological changes in the thyroid glands of the control group. The mean thyroid volume did not significantly change during pregnancy and after delivery in both the patient group and controls. The mean thyroid volume was smaller in the study group, with 7.55 ml (SD 6.01) compared to the controls with 11.29 ml (SD 5.61), a difference which was not statistically significant. Neither course of pregnancy nor fetal outcome was influenced by inactive autoimmune disease of the thyroid.
对9名诊断为自身免疫性甲状腺疾病的孕妇在孕期定期进行检查，并在产后两个月进行研究，检测其甲状腺功能及超声测定的甲状腺体积。将结果与10名健康孕妇的检查结果进行比较。在超声检查中，7名患者出现了明确的形态学改变，如甲状腺回声减低和不均匀，但在孕期及产后8周内均未发生变化。对照组甲状腺未出现形态学改变。患者组和对照组的平均甲状腺体积在孕期和产后均无显著变化。研究组的平均甲状腺体积较小，为7.55 ml（标准差6.01），而对照组为11.29 ml（标准差5.61），差异无统计学意义。甲状腺非活动性自身免疫疾病对妊娠过程及胎儿结局均无影响。
