Ueda G, Fujita M, Ogawa H, Sawada M, Inoue M, Tanizawa O
Department of Obstetrics and Gynecology, Osaka University Medical School, Japan.
Gynecol Oncol. 1993 Feb;48(2):259-63. doi: 10.1006/gyno.1993.1044.
We report a case of adenocarcinoma associated with benign cystic teratoma (dermoid cyst) of the ovary in which the patient has survived for a long time. A 62-year-old woman underwent abdominal total hysterectomy with bilateral salpingo-oophorectomy on March 16, 1976 because of a large left ovarian tumor. There were no pathologic findings in other intra-abdominal organs. The tumor was cystic, contained dark and mucinous sebaceous material with hair, and weighed 15 kg. Papillary growths protruded into the cavity in some areas of the wall. Microscopically and immunohistochemically, the tumor was characterized as a mucinous adenocarcinoma associated with dermoid cyst, suggesting a possible gastrointestinal origin. After the surgery, she was treated with chemotherapy and is alive and well more than 15 years later. Our review of the literature indicates that, while it is widely held that patients with adenocarcinoma associated with dermoid cyst do not survive, many in fact do survive for a long period after surgery.
我们报告一例卵巢腺癌合并良性囊性畸胎瘤（皮样囊肿）患者，该患者已长期存活。一名62岁女性因左卵巢巨大肿瘤于1976年3月16日接受了腹式全子宫切除术及双侧输卵管卵巢切除术。腹腔内其他器官未发现病理改变。肿瘤为囊性，内含深色黏液性皮脂样物质及毛发，重15千克。在囊壁某些区域有乳头状突起伸向腔内。显微镜及免疫组化检查显示，该肿瘤为黏液性腺癌合并皮样囊肿，提示可能起源于胃肠道。术后她接受了化疗，15年多后仍健在且状况良好。我们对文献的回顾表明，虽然普遍认为腺癌合并皮样囊肿的患者无法存活，但实际上许多患者术后确实能长期存活。
