Kallakury B V, Bui H X, delRosario A, Wallace J, Solis O G, Ross J S
Department of Pathology and Laboratory Medicine, Albany Medical College, NY 12208.
Arch Pathol Lab Med. 1993 Mar;117(3):299-301.
We describe the first case, to our knowledge, of a primary gastric adenosarcoma surgically resected from a 46-year-old white man. This biphasic neoplasm, well described in the female genital tract, was composed of cytologically benign tubular and cystic glands widely dispersed within a sarcomatous stromal component. Immunohistochemically, the epithelial elements were positive for cytokeratin, while the stromal elements were positive for vimentin and desmin. The clinical and pathologic features of pelvic adenosarcomas are described and compared with the tumor of the stomach. Although accurate prediction of the biologic behavior of this gastric neoplasm is difficult, the high mitotic rate in the sarcomatous component and the infiltration of the gastric serosal surface by the tumor were considered to be ominous prognostic features.
据我们所知，我们描述了首例经手术切除的原发性胃腺肉瘤病例，患者为一名46岁的白人男性。这种双相性肿瘤在女性生殖道中已有详细描述，由细胞学上良性的管状和囊性腺体组成，广泛分布于肉瘤样间质成分中。免疫组化显示，上皮成分细胞角蛋白阳性，而间质成分波形蛋白和结蛋白阳性。本文描述了盆腔腺肉瘤的临床和病理特征，并与胃肿瘤进行了比较。尽管难以准确预测这种胃肿瘤的生物学行为，但肉瘤成分中的高有丝分裂率以及肿瘤对胃浆膜面的浸润被认为是预后不良的特征。
