Zelck U, Karnstedt U
Institut für Pharmakologie und Toxikologie, Medizinischen Fakultät der Universität Rostock.
Z Gesamte Inn Med. 1993 Feb;48(2):78-81.
From 20 patients with acute pancreatitis the activities of the antioxidative enzymes glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) were estimated in the blood serum immediately before and during therapy with sodium selenite. The results demonstrate significant (p < 0.01 respectively < 0.05) enhanced activities of GSH-Px under the selenite therapy. Serum SOD activities were not significant influenced by the selenium treatment. The results obtained were not dependent on the reference basis (units/mg protein or U/l serum) used.
对20例急性胰腺炎患者，在亚硒酸钠治疗前及治疗期间即刻测定其血清中抗氧化酶谷胱甘肽过氧化物酶（GSH-Px）和超氧化物歧化酶（SOD）的活性。结果显示，亚硒酸钠治疗后GSH-Px活性显著增强（分别为p < 0.01和p < 0.05）。血清SOD活性不受硒治疗的显著影响。所获结果不依赖于所采用的参考基准（单位/毫克蛋白质或单位/升血清）。
