D'iakova S D, Rudenko L P
Zh Vyssh Nerv Deiat Im I P Pavlova. 1993 Jan-Feb;43(1):42-54.
Under the influence of diazepam in doses of 0.2-2.0 mg/kg in a situation of different probability and value of a reinforcement the dogs--sanguinics and melancholics change their strategy of behavior, from the preference at norm of a reinforcement of the low probability but the better quality to that of the high probability but the worse quality. Under the same conditions the strategy of behaviour of cholerics and phlegmatics practically does not change. The change of behaviour strategy under the influence of diazepam in sanguinics and melancholics is proposed to be connected with a depressing effect of the drug on the hippocampus and amygdala and simultaneous activation of the hypothalamus and the frontal cortex. The data obtained are discussed from the position of P. V. Simonov's concept on the four above-mentioned brain macrostructures as the basis of the type of the higher nervous activity and behaviour of animals and man.
在不同强化概率和价值的情况下,给予剂量为0.2 - 2.0毫克/千克的地西泮,血液型和胆汁质的狗会改变其行为策略,从偏好低概率但质量较好的强化方式转变为高概率但质量较差的强化方式。在相同条件下,胆汁质和黏液质的行为策略实际上没有变化。血液型和胆汁质受地西泮影响而发生的行为策略变化,被认为与该药物对海马体和杏仁核的抑制作用以及下丘脑和额叶皮质的同时激活有关。从P. V. 西蒙诺夫关于上述四种脑宏观结构作为动物和人类高级神经活动及行为类型基础的概念角度,对所获得的数据进行了讨论。