Reide W, Dost P, Missfeldt N, Heine J, Jahnke K
Universitäts-HNO-Klinik Essen.
HNO. 1993 Mar;41(3):131-4.
In this study we examined the feasibility of rebuilding a stable stapes superstructure for a new articulated ossicular chain by using bioactive ceramics. Dense hydroxylapatite and ceravital were tested in guinea pigs. The ceramic prosthesis was placed on the remnants of the footplate to create a bony connection without touching the tympanic membrane, thereby protecting it from relative movements. The implants were explanted together with the stapes footplate at six weeks and three months, respectively. Histologically, bony connections were found between all ceramic implants and the remnants of the crura even at six weeks and became more pronounced after three months.
在本研究中,我们探讨了使用生物活性陶瓷为新的关节听骨链重建稳定镫骨上部结构的可行性。在豚鼠身上测试了致密羟基磷灰石和西拉维它(商品名)。将陶瓷假体放置在镫骨足板残余部分上,以建立骨连接,且不接触鼓膜,从而保护鼓膜免受相对运动影响。分别在六周和三个月时将植入物与镫骨足板一起取出。组织学检查发现,即使在六周时,所有陶瓷植入物与脚间骨残余之间就已形成骨连接,三个月后更为明显。