Reck R, Helms J
Am J Otol. 1985 May;6(3):280-3.
Since 1979, various ceramics have been recommended as valuable implant materials in tympanoplasties. Such implants are used for the reconstruction of the ossicular chain or the posterior canal wall. Animal studies on bioinert and bioactive ceramics in the middle ear have been carried out to confirm their biocompatibility. Histologic and clinical findings have made it obvious that aluminum- or borum-aluminum oxide ceramics are well tolerated in the middle ear and may produce functional results, provided they are separated from the tympanic membrane or the footplate of the stapes by an interposition of cartilage. Porous tricalcium phosphate ceramics cannot be recommended for the reconstruction of the ossicular chain because they are degradable, but they may be useful for the obliteration of small mastoid cavities. Our five-year histologic and clinical experience with the bioactive glass ceramic Ceravital revealed in 1983 that this material is suitable for the reconstruction of the ossicular chain as well as of the posterior canal wall, without the need for protection by cartilage. Ceravital implants in fact behave like homologous ossicles.
自1979年以来,各种陶瓷材料被推荐作为鼓室成形术中的重要植入材料。此类植入物用于重建听骨链或后鼓室壁。已经开展了关于中耳生物惰性和生物活性陶瓷的动物研究,以证实其生物相容性。组织学和临床研究结果表明,氧化铝或硼氧化铝陶瓷在中耳具有良好的耐受性,并且如果通过软骨隔离使其与鼓膜或镫骨足板分离,则可能产生功能性效果。多孔磷酸三钙陶瓷不适合用于重建听骨链,因为它们可降解,但它们可能有助于封闭小乳突腔。我们在1983年公布的对生物活性玻璃陶瓷Ceravital的五年组织学和临床经验表明,这种材料适用于重建听骨链以及后鼓室壁,无需软骨保护。事实上,Ceravital植入物的表现类似于同种听小骨。