Moriyama Y, Saigenzi H, Shimokawa S, Umebayashi Y, Toyohira H, Hashiguchi M, Taira A
Second Department of Surgery, Kagoshima University Faculty of Medicine, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1993 Mar;41(3):367-71.
Thirty-four cases of primary cardiac tumors, consisted of 11 men and 23 women, aged between 26 and 80 years have been operated on in our institution. A total of 30 myxomas and four malignant tumors were resected. The clinical presentations included congestive heart failure in 25 patients, tachyarrhythmia in 6, chest pain in 4, and embolism in 10. All 30 myxoma lesions were completely resected, although none of the malignant tumors could be resected completely because of invasion of the tumor to the surrounding tissues. Four patients with malignant tumors died of tumor recurrence within 9 months after operation. Histological diagnosis was rhabdomyosarcoma in two patients, round cell sarcoma in one and malignant fibrous histiocytoma in one. All patients with myxoma survived operation. Follow-up was completed in 28 patients (range 1 month to 15 years, mean 5.5 years): Twenty-four were in New York Heart Association Class I, and the remaining two in Class II. Actuarial survival rate was 89% at 15 years after operation. No recurrent myxoma have been identified clinically or by echocardiography. For malignant primary tumors, more effective adjuvant therapy with aggressive resection will be inevitable to improve long-term prognosis.
我院共对34例原发性心脏肿瘤患者进行了手术，其中男性11例，女性23例，年龄在26至80岁之间。共切除30例黏液瘤和4例恶性肿瘤。临床表现包括25例充血性心力衰竭、6例快速心律失常、4例胸痛和10例栓塞。所有30例黏液瘤病变均被完全切除，然而由于肿瘤侵犯周围组织，4例恶性肿瘤均无法完全切除。4例恶性肿瘤患者术后9个月内死于肿瘤复发。组织学诊断为2例横纹肌肉瘤、1例圆形细胞肉瘤和1例恶性纤维组织细胞瘤。所有黏液瘤患者术后存活。28例患者完成随访（范围1个月至15年，平均5.5年）：24例为纽约心脏协会I级，其余2例为II级。术后15年的精算生存率为89%。临床或超声心动图均未发现复发性黏液瘤。对于原发性恶性肿瘤，积极切除并采用更有效的辅助治疗对于改善长期预后将是必不可少的。
