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心脏手术联合肺切除术

Cardiac operation with associated pulmonary resection.

作者信息

Yokoyama T, Derrick M J, Lee A W

机构信息

Pacific Cardiothoracic Surgery Group, St. Vincent Medical Center, Los Angeles, Calif.

出版信息

J Thorac Cardiovasc Surg. 1993 May;105(5):912-6; discussion 916-7.

PMID:8387618
Abstract

From February 1988 to May 1992, a total of 11 patients aged 52 to 81 years underwent concomitant cardiac operation and pulmonary resection for bronchogenic carcinoma at our institution. All pulmonary lesions were incidental findings on preoperative chest x-ray films. Diagnosis was obtained in six patients before resection. The operation was performed through a midline sternotomy with all patients requiring cardiopulmonary bypass. Pulmonary procedures included two wedge resections, seven lobectomies, and two double lobectomies. Seven patients underwent lobectomy while supported by bypass, with the lungs collapsed, during rewarming. Total bypass time for these patients averaged 143 minutes. Pathologic examination showed all lesions to be non-small-cell malignant tumors; four adenocarcinomas, four squamous cell carcinomas, two bronchoalveolar carcinomas, and one undifferentiated carcinoma. Nine were stage I and two were stage II. One of the wedge resections showed malignant disease involving the surgical margin that later required completion lobectomy. There were no operative deaths and no major postoperative complications. Postoperative hospital stays ranged from 6 to 17 days (mean 10 days) except for one patient who required a prolonged hospitalization because of a complication after thoracentesis on the side opposite the pulmonary resection. Concomitant cardiac operations with lobectomy can be safely performed during cardiopulmonary bypass without significantly prolonging pump time. Our observations suggest that concomitant cardiac surgery with pulmonary resection is a safe and effective technique with minimal morbidity and short hospital stay.

摘要

1988年2月至1992年5月,我院共有11例年龄在52至81岁之间的患者因支气管源性肺癌接受了心脏手术与肺切除术。所有肺部病变均为术前胸部X光片的偶然发现。6例患者在切除术前得以确诊。手术通过正中胸骨切开术进行,所有患者均需体外循环。肺部手术包括2例楔形切除术、7例肺叶切除术和2例双肺叶切除术。7例患者在体外循环支持下、肺萎陷状态下复温过程中接受了肺叶切除术。这些患者的体外循环总时间平均为143分钟。病理检查显示所有病变均为非小细胞恶性肿瘤;4例腺癌、4例鳞状细胞癌、2例细支气管肺泡癌和1例未分化癌。9例为I期,2例为II期。其中1例楔形切除术显示恶性病变累及手术切缘,随后需要完成肺叶切除术。无手术死亡病例,也无重大术后并发症。术后住院时间为6至17天(平均10天),但有1例患者因肺切除对侧胸腔穿刺术后出现并发症而需要延长住院时间。在体外循环期间,可以安全地进行肺叶切除术与心脏手术,而不会显著延长体外循环时间。我们的观察结果表明,心脏手术与肺切除术联合是一种安全有效的技术,发病率极低且住院时间短。

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