Brown J K
Oncol Nurs Forum. 1993 Apr;20(3):466-72.
The purpose of this study was to examine the relationships of gender, age, usual weight, and tobacco use with cancer-related weight loss, food intake, and resting energy expenditure. Data were collected from medical records, interviews, self-report diet records, indirect calorimetry, and 40K counting. A convenience sample consisted of 60 subjects with non-small cell lung cancer who were at least one month postradiotherapy. Mean weight loss was 2 kg at diagnosis and 6 kg at six weeks postradiotherapy. Partial correlations, controlling for stage of disease, indicated that gender, age, and current smoking correlate significantly with cancer-related weight loss and decreased food intake. Gender, age, and current smoking accounted for 21% of the variance of weight loss postradiotherapy over and above stage of disease. Potential practice implications focus on enhanced nutritional assessment and early intervention for men, the elderly, and current smokers, who are at higher risk for weight loss.
本研究的目的是探讨性别、年龄、通常体重和烟草使用与癌症相关体重减轻、食物摄入量及静息能量消耗之间的关系。数据收集自病历、访谈、自我报告饮食记录、间接测热法和40K计数。一个便利样本由60名非小细胞肺癌患者组成，这些患者至少在放疗后一个月。诊断时平均体重减轻2千克，放疗后六周时平均体重减轻6千克。在控制疾病分期的情况下进行的偏相关分析表明，性别、年龄和当前吸烟状况与癌症相关体重减轻及食物摄入量减少显著相关。性别、年龄和当前吸烟状况在疾病分期之外，还占放疗后体重减轻方差的21%。潜在的实践意义集中在对男性、老年人和当前吸烟者加强营养评估和早期干预，这些人群体重减轻风险较高。
