Bols A, Janssens J, Peetermans W, Stevens E, Bobbaers H
Department of General Internal Medicine, University Hospitals, K. U. Leuven, Belgium.
Acta Clin Belg. 1993;48(1):42-7. doi: 10.1080/17843286.1993.11718283.
A congenital C5 deficiency was the cause of recurrent meningococcal disease in a 27-year-old man. The lack of serum bactericidal activity accounts for the higher incidence and the different course of Neisseria infections in patients with a deficiency of the late complement components. Early antibiotic treatment and vaccination with a capsular polysaccharide meningococcal vaccine (A,C,Y,W-135) should be considered.
一名27岁男性反复发生脑膜炎球菌病，病因是先天性C5缺乏。血清杀菌活性缺乏解释了补体晚期成分缺乏患者中奈瑟菌感染的较高发病率和不同病程。应考虑早期抗生素治疗和接种结合多糖脑膜炎球菌疫苗（A、C、Y、W-135）。
