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Functional correlation between the Ser/Thr-phosphorylation of band-3 and band-3-mediated transmembrane anion transport in human erythrocytes.

作者信息

Baggio B, Bordin L, Clari G, Gambaro G, Moret V

机构信息

Istituto di Medicina Interna, Università di Padova, Italy.

出版信息

Biochim Biophys Acta. 1993 May 14;1148(1):157-60. doi: 10.1016/0005-2736(93)90173-w.

DOI:10.1016/0005-2736(93)90173-w
PMID:8388726
Abstract

In human erythrocytes, okadaic acid, a potent inhibitor of certain protein phosphatases, promotes a marked increase of Ser/Thr-phosphorylation of membrane proteins, including band-3 protein. Moreover, okadaic acid also increases the band-3-mediated oxalate transport across the membranes, thus suggesting that this process is regulated by Ser/Thr-phosphorylation of transporter band-3 protein.

摘要

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