Palmer G
Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77251-1892.
J Bioenerg Biomembr. 1993 Apr;25(2):145-51. doi: 10.1007/BF00762856.
Some contemporary issues relevant to the chemistry of mammalian cytochrome c oxidase are discussed. These include the optical properties of heme A and the spectroscopic consequences of the differences in side-chain substitution compared to heme B; a common fallacy concerning the electrostatic exchange interaction between cytochrome a3 and CuB; the question of the number and location of the copper components of the enzyme; and the mode of binding of ligands such as cyanide and azide.
讨论了一些与哺乳动物细胞色素c氧化酶化学相关的当代问题。这些问题包括血红素A的光学性质以及与血红素B相比侧链取代差异的光谱学后果；关于细胞色素a3和CuB之间静电交换相互作用的一个常见错误观念；该酶铜组分的数量和位置问题；以及氰化物和叠氮化物等配体的结合模式。
