Scott S D, Smith G D, Ross N L, Binns M M
AFRC Institute for Animal Health, Houghton Laboratory, Cambridgeshire, U.K.
J Gen Virol. 1993 Jun;74 ( Pt 6):1185-90. doi: 10.1099/0022-1317-74-6-1185.
The glycoprotein H (gH) genes of two avian herpesviruses, Marek's disease virus and the herpesvirus of turkeys, have been cloned and sequenced and the coding regions found to be of 2439 and 2424 nucleotides respectively. The predicted primary polypeptide products of these open reading frames are 813 and 808 amino acids and correspond to Mrs of 90,800 and 91,100. Both amino acid sequences exhibit characteristic glycoprotein features such as hydrophobic signal and anchor sequences and potential sites for N-linked glycosylation. Polypeptide sequence comparison to the other eight available gH sequences revealed more similarity to the alphaherpesvirus subgroup than to either beta- or gammaherpesviruses.
两种禽疱疹病毒，即马立克氏病病毒和火鸡疱疹病毒的糖蛋白H（gH）基因已被克隆和测序，发现其编码区分别为2439和2424个核苷酸。这些开放阅读框预测的初级多肽产物分别为813和808个氨基酸，对应的分子量为90,800和91,100。两种氨基酸序列均表现出典型的糖蛋白特征，如疏水信号和锚定序列以及N-连接糖基化的潜在位点。与其他八个可用的gH序列进行多肽序列比较发现，与α疱疹病毒亚组的相似性高于β或γ疱疹病毒。
