杆状病毒载体在昆虫细胞中以及感染1型马立克氏病病毒（MDV1）的鸡胚成纤维细胞中表达一种新型MDV1特异性蛋白p40。
Expression of a novel Marek's disease virus type 1 (MDV1)-specific protein p40 in insect cells by a baculovirus vector and in chick embryo fibroblasts infected with MDV1.
作者信息
Urakawa T, Sakaguchi M, Yamamoto M, Zhu G S, Hirai K
机构信息
Chemo-Sero Therapeutic Research Institute, Kikuchi Research Center, Japan.
出版信息
Arch Virol. 1994;137(1-2):191-7. doi: 10.1007/BF01311187.
PMID:7979993
Abstract
We found that the open reading frame of 1053 nucleotides within the short unique sequence of Marek's disease virus (MDV) type 1 (MDV1) expresses a 40 kDa protein, using a baculovirus vector in insect cells. Mouse antisera against the 40 kDa protein reacted with a 40 kDa protein in MDV1-infected cells. A cross-reactive polypeptide of 37 kDa was also detected in cells infected with herpesvirus of turkey.
摘要
我们发现，使用杆状病毒载体在昆虫细胞中，1型马立克氏病病毒（MDV1）短独特序列内1053个核苷酸的开放阅读框表达一种40 kDa的蛋白质。针对该40 kDa蛋白质的小鼠抗血清与MDV1感染细胞中的一种40 kDa蛋白质发生反应。在感染火鸡疱疹病毒的细胞中也检测到一种37 kDa的交叉反应性多肽。
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