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用重组人促红细胞生成素治疗透析前患者的费用。

Cost of treating predialysis patients with recombinant human erythropoietin.

作者信息

Durand-Zaleski I, Goldfarb B, Blum-Boisgard C, Drüeke T, Kreis H

机构信息

Département de Santé Publique, Faculté de Médecine Créteil Val de Marne, France.

出版信息

Nephrol Dial Transplant. 1993;8(4):311-4.

PMID:8390004
Abstract

Treatment of the anaemia of predialysis patients with recombinant human erythropoietin (rHuEpo) is likely to become a widely accepted practice during the coming years. We estimated the impact on health care expenditures with the example of the French population of end-stage renal disease patients. Using retrospective data, we calculated the percentage of predialysis patients with advanced chronic renal failure who would be eligible for treatment according to two different criteria based on haemoglobin and clinical condition, the total duration of treatment, and the total amount of rHuEpo delivered. We estimate that the total cost of treating French predialysis patients could vary between 2.2 and 6.5 million Swiss francs, or 50,000 to 140,000 Swiss francs per million population, using rHuEpo dosage from 50 to 150 IU/kg week.

摘要

在未来几年,使用重组人促红细胞生成素(rHuEpo)治疗透析前患者的贫血可能会成为一种被广泛接受的做法。我们以法国终末期肾病患者群体为例,估算了其对医疗保健支出的影响。利用回顾性数据,我们根据血红蛋白和临床状况这两个不同标准,计算了晚期慢性肾衰竭透析前患者中符合治疗条件的患者百分比、治疗总时长以及rHuEpo的给药总量。我们估计,使用每周50至150国际单位/千克的rHuEpo剂量,治疗法国透析前患者的总成本可能在220万至650万瑞士法郎之间,即每百万人口5万至14万瑞士法郎。

相似文献

1
Cost of treating predialysis patients with recombinant human erythropoietin.用重组人促红细胞生成素治疗透析前患者的费用。
Nephrol Dial Transplant. 1993;8(4):311-4.
2
Evolution of recombinant human erythropoietin usage in clinical practice in the United States. Is there an optimal way to use rHuEPO?美国临床实践中重组人促红细胞生成素使用情况的演变。是否存在使用重组人促红细胞生成素的最佳方式?
ASAIO J. 1993 Jan-Mar;39(1):11-8.
3
Treatment of the anaemia of end-stage renal disease with recombinant human erythropoietin.
Neth J Med. 1988 Aug;33(1-2):60-7.
4
The use of recombinant human erythropoietin (rHuEpo) in humans.
Cancer Surv. 1990;9(1):157-67.
5
[Pharmacokinetics and clinical effect of recombinant human erythropoietin on the anemia of predialysis patients].
Nihon Jinzo Gakkai Shi. 1992 Jun;34(6):701-10.
6
Recombinant human erythropoietin (rHuEPO) in the treatment of anaemia of chronic renal failure.
J Assoc Physicians India. 1991 Jun;39(6):483-5.
7
[Recombinant human erythropoietin in the treatment of the anemia of multiple myeloma with kidney failure].重组人促红细胞生成素治疗合并肾衰竭的多发性骨髓瘤贫血
An Med Interna. 1995 Apr;12(4):187-8.
8
[Use of human recombinant erythropoietin (rHuEPO) for treatment of anemia in patients with chronic kidney failure who don't require additional dialysis therapy].[使用重组人促红细胞生成素(rHuEPO)治疗无需额外透析治疗的慢性肾衰竭患者的贫血]
Przegl Lek. 1995;52(3):93-4.
9
[Evaluation of treating anemia in patients undergoing chronic dialysis with small doses of human recombinant erythropoietin].
Pol Tyg Lek. 1995 Oct;50(40-44):15-8, 31.
10
Factors influencing anaemia in dialysis patients. A special survey by the EDTA-ERA Registry.
Nephrol Dial Transplant. 1993;8(7):585-9.

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Drugs. 1996 Feb;51(2):299-318. doi: 10.2165/00003495-199651020-00008.