致癌物苯并[a]芘的高致突变性7,8-二醇9,10-环氧化物的合成与反应 - Suppr

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Synthesis and reactions of the highly mutagenic 7,8-diol 9,10-epoxides of the carcinogen benzo[a]pyrene.

作者信息

Yagi H, Thakker D R, Hernandez O, Koreeda M, Jerina D M

出版信息

J Am Chem Soc. 1977 Mar 2;99(5):1604-11. doi: 10.1021/ja00447a053.

DOI:10.1021/ja00447a053

PMID:839009

Abstract

摘要

相似文献

Synthesis and reactions of the highly mutagenic 7,8-diol 9,10-epoxides of the carcinogen benzo[a]pyrene.致癌物苯并[a]芘的高致突变性7,8-二醇9,10-环氧化物的合成与反应

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Mutagenicity and cytotoxicity of benzo(a)pyrene benzo-ring epoxides.苯并(a)芘苯环环氧化物的致突变性和细胞毒性。

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Absolute sterochemistry of the highly mutagenic 7,8-diol 9,10-epoxides derived from the potent carcinogen trans-7,8-dihydroxy-7,8-dihydrobenzol[a]pyrene.源自强效致癌物反式-7,8-二羟基-7,8-二氢苯并[a]芘的高致突变性7,8-二醇9,10-环氧化物的绝对立体化学。

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Differences in mutagenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides.非对映体苯并[a]芘7,8-二醇-9,10-环氧化物光学对映体的诱变性差异。

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