Holstein A F
Department of Microscopical Anatomy, University of Hamburg, FRG.
Eur Urol. 1993;23 Suppl 2:9-18. doi: 10.1159/000474693.
Different types of tumor cells can be described by means of the semithin section method, immunocytochemistry and transmission electron microscopy. They are situated intratubularly in the basal and adluminal compartment of the germinal epithelium, in the interstitium, and in the solid seminoma. Also teratoma cells can be identified within the seminiferous tubules. Their occurrence together with tumor cells, rich in glycogen (Tc 1), in the same area of a seminiferous tubule, supports the suggestion that seminomata and teratomata originate from the same tumor cell type. Macrophages may be an essential constituent of the early forms of testicular tumors. They are able to invade seminiferous tubules, there to lyse tumor cells and to phagocytose them in fragments. The different participation of the particular cell systems in a testicular tumor is decisive for its organization and presentation.
不同类型的肿瘤细胞可以通过半薄切片法、免疫细胞化学和透射电子显微镜来描述。它们位于生精上皮的基底和近腔区的小管内、间质以及实体性精原细胞瘤中。在曲细精管内也可以识别出畸胎瘤细胞。它们与富含糖原的肿瘤细胞（Tc 1）在曲细精管的同一区域同时出现，支持了精原细胞瘤和畸胎瘤起源于同一肿瘤细胞类型的观点。巨噬细胞可能是睾丸肿瘤早期形式的重要组成部分。它们能够侵入曲细精管，在那里裂解肿瘤细胞并吞噬其碎片。特定细胞系统在睾丸肿瘤中的不同参与情况对其组织结构和表现起着决定性作用。
