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父母离异与青少年的神经内分泌变化

Parental divorce and neuroendocrine changes in adolescents.

作者信息

Gerra G, Caccavari R, Delsignore R, Passeri M, Fertonani Affini G, Maestri D, Monica C, Brambilla F

机构信息

Drug Addiction Service, Hospital of Parma, Italy.

出版信息

Acta Psychiatr Scand. 1993 May;87(5):350-4. doi: 10.1111/j.1600-0447.1993.tb03385.x.

DOI:10.1111/j.1600-0447.1993.tb03385.x
PMID:8390775
Abstract

Plasma noradrenaline (NE), adrenocorticotrophic hormone (ACTH), growth hormone (GH), prolactin (PRL) and luteinizing hormone (LH) concentrations were examined in basal conditions and after stimulation by the step test in two groups of psychophysically healthy adolescent girls, 18 from divorced families and 16 from non-divorced families. Basal NE, ACTH, GH, PRL values did not differ in the two groups, whereas those of LH were significantly lower in the adolescents from divorced parents than in those from non-divorced families. Responses of NE and ACTH to the stimulus were normal, of GH and PRL were weaker, and of LH slightly weaker in children of divorced parents. An impaired catecholaminergic and serotoninergic tonus in children of disrupted families might underly the hormonal alterations.

摘要

对两组身心健康的青春期女孩进行了研究,一组18名来自离异家庭,另一组16名来自非离异家庭,检测了她们在基础状态下以及进行阶梯试验刺激后的血浆去甲肾上腺素(NE)、促肾上腺皮质激素(ACTH)、生长激素(GH)、催乳素(PRL)和黄体生成素(LH)浓度。两组的基础NE、ACTH、GH、PRL值没有差异,而来自离异家庭的青少年的LH值显著低于来自非离异家庭的青少年。离异家庭孩子的NE和ACTH对刺激的反应正常,GH和PRL的反应较弱,LH的反应稍弱。家庭破裂的孩子中儿茶酚胺能和5-羟色胺能张力受损可能是激素改变的基础。

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