Xia Y R, Klisak I, Sparkes R S, Oram J, Lusis A J
Department of Medicine, University of California, Los Angeles 90024.
Genomics. 1993 May;16(2):524-5. doi: 10.1006/geno.1993.1221.
The high-density lipoprotein binding protein (HDLbp) is a 110-kDa protein that specifically binds HDL molecules and may function in the removal of excess cellular cholesterol. As part of an effort to study the function of the protein and its possible role in cholesterol transport, we report the localization of the gene for HDLbp, designated HDLBP, to human chromosome 2q37 using analysis of somatic cell hybrids and in situ hybridization.
高密度脂蛋白结合蛋白（HDLbp）是一种110千道尔顿的蛋白质，它能特异性结合HDL分子，并可能在清除细胞内多余胆固醇的过程中发挥作用。作为研究该蛋白质功能及其在胆固醇转运中可能作用的一部分，我们通过体细胞杂交分析和原位杂交，报告了HDLbp基因（命名为HDLBP）定位于人类染色体2q37。
