在与川崎病样冠状动脉瘤相关的慢性活动性爱泼斯坦-巴尔病毒感染的心脏和主动脉组织中检测爱泼斯坦-巴尔病毒DNA。
Detection of Epstein-Barr virus DNA in cardiac and aortic tissues from chronic, active Epstein-Barr virus infection associated with Kawasaki disease-like coronary artery aneurysms.
作者信息
Kikuta H, Sakiyama Y, Matsumoto S, Hamada I, Yazaki M, Iwaki T, Nakano M
机构信息
Department of Pediatrics, Hokkaido University School of Medicine, Sapporo, Japan.
出版信息
J Pediatr. 1993 Jul;123(1):90-2. doi: 10.1016/s0022-3476(05)81546-x.
We describe three patients with chronic, active Epstein-Barr virus infection associated with Kawasaki disease-like coronary artery aneurysms. The Epstein-Barr virus genome was detected in three cardiac tissue samples and one aortic tissue sample examined by means of the polymerase chain reaction. These findings suggest that chronic Epstein-Barr virus infection may play a pathogenic role in the development of coronary artery aneurysms.
我们描述了三名患有慢性活动性爱泼斯坦-巴尔病毒感染并伴有川崎病样冠状动脉瘤的患者。通过聚合酶链反应检测，在三个心脏组织样本和一个主动脉组织样本中发现了爱泼斯坦-巴尔病毒基因组。这些发现表明，慢性爱泼斯坦-巴尔病毒感染可能在冠状动脉瘤的发生发展中起致病作用。
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