Pitre J, Houssin D, Kracht M
Clinique Chirurgicale Hôpital Cochin, Paris.
Gastroenterol Clin Biol. 1993;17(3):200-6.
In order to identify the prognostic factors of the resection of hepatocellular carcinoma, the results of 153 resections performed between January 1984 and December 1988 in 18 French centers were analysed. Cirrhosis was present in 76% of the patients. Among the postoperative complications (61%), the most frequent were ascites (35.3%) and liver failure (19%). Operative mortality was 20%. One-, 3- and 5-year survival rates were 52.7, 30.1, and 17.9%, respectively. The survival rate was significantly higher in patients with a curative resection, Pugh's class A or with a tumor less than 3 centimeters in diameter. After curative resection, actuarial survival rates without recurrence were 65, 24.4, and 16.7% after, 1, 3, and 4 years respectively. In this case, the survival rate was significantly related to the number of resected nodules and the size of the tumor but not to the presence of a capsule surrounding the tumor.
为了确定肝细胞癌切除术的预后因素，对1984年1月至1988年12月间法国18个中心进行的153例切除术的结果进行了分析。76%的患者存在肝硬化。在术后并发症（61%）中，最常见的是腹水（35.3%）和肝衰竭（19%）。手术死亡率为20%。1年、3年和5年生存率分别为52.7%、30.1%和17.9%。根治性切除、普格分级为A类或肿瘤直径小于3厘米的患者生存率明显更高。根治性切除后，1年、3年和4年后无复发的精算生存率分别为65%、24.4%和16.7%。在这种情况下，生存率与切除结节的数量和肿瘤大小显著相关，但与肿瘤周围包膜的存在无关。
