Vekshina N L, Khristoliubova N A
Eksp Klin Farmakol. 1993 Mar-Apr;56(2):58-60.
The study was undertaken to examine two-week and two-month rats whose mothers had been given alcohol for a long period of time during pregnancy and lactation. Profound changes were found in the properties of all types of the receptors under study. The changes were found in the receptors of both group animals. Substantial changes were encountered in the properties of GABA and DA2 receptors in the brain of two-month rats after acute alcoholization. The changes were differentiated from those seen in GABA and DA2 receptors in the brain of the rats whose mothers had not been given ethanol.
该研究旨在检查两组大鼠，一组为出生两周的，另一组为出生两个月的，它们的母亲在怀孕和哺乳期长期摄入酒精。研究发现，所有类型的受体内性质都发生了显著变化。两组动物的受体均出现了这种变化。急性酒精中毒后，两个月大的大鼠大脑中GABA和DA2受体的性质发生了实质性变化。这些变化与未给其母亲喂食乙醇的大鼠大脑中GABA和DA2受体的变化不同。
