具有生物活性的中氮茚衍生物I：中氮茚-2-羧酸的N'-取代酰肼
Indolizine derivatives with biological activity I: N'-substituted hydrazides of indolizine-2-carboxylic acid.
作者信息
Cardellini M, Claudi F, Grifantini M, Gulini U, Martelli S
出版信息
J Pharm Sci. 1977 Feb;66(2):259-62. doi: 10.1002/jps.2600660230.
PMID:839424
Abstract
The synthesis and antimonoamine oxidase activity of some N'-substituted hydrazides of indolizine-2-carboxylic acid are described. They all inhibit monoamine oxidase and are more active than iproniazid. The structure-activity relationships also are discussed.
摘要
描述了中氮茚-2-羧酸的一些N'-取代酰肼的合成及抗单胺氧化酶活性。它们均能抑制单胺氧化酶，且比异烟肼更具活性。还讨论了构效关系。
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